Scandcleft Project Trial 3 – comparison of speech outcomes in relation to sequence in twostage palatal repair procedures in 5-year-olds with unilateral cleft lip and palate

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Standard

Scandcleft Project Trial 3 – comparison of speech outcomes in relation to sequence in twostage palatal repair procedures in 5-year-olds with unilateral cleft lip and palate. / Persson , Christina; Davies, Julie; Willadsen, Elisabeth; Bowden, Melanie ; Hayden, Christine ; Aukner, Ragnhild ; Pedersen, Nina Helen.

I: Cleft Palate - Craniofacial Journal, 2020, s. 352-363.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Persson , C, Davies, J, Willadsen, E, Bowden, M, Hayden, C, Aukner, R & Pedersen, NH 2020, 'Scandcleft Project Trial 3 – comparison of speech outcomes in relation to sequence in twostage palatal repair procedures in 5-year-olds with unilateral cleft lip and palate', Cleft Palate - Craniofacial Journal, s. 352-363. https://doi.org/10.1177/1055665619896637

APA

Persson , C., Davies, J., Willadsen, E., Bowden, M., Hayden, C., Aukner, R., & Pedersen, N. H. (2020). Scandcleft Project Trial 3 – comparison of speech outcomes in relation to sequence in twostage palatal repair procedures in 5-year-olds with unilateral cleft lip and palate. Cleft Palate - Craniofacial Journal, 352-363. https://doi.org/10.1177/1055665619896637

Vancouver

Persson C, Davies J, Willadsen E, Bowden M, Hayden C, Aukner R o.a. Scandcleft Project Trial 3 – comparison of speech outcomes in relation to sequence in twostage palatal repair procedures in 5-year-olds with unilateral cleft lip and palate. Cleft Palate - Craniofacial Journal. 2020;352-363. https://doi.org/10.1177/1055665619896637

Author

Persson , Christina ; Davies, Julie ; Willadsen, Elisabeth ; Bowden, Melanie ; Hayden, Christine ; Aukner, Ragnhild ; Pedersen, Nina Helen. / Scandcleft Project Trial 3 – comparison of speech outcomes in relation to sequence in twostage palatal repair procedures in 5-year-olds with unilateral cleft lip and palate. I: Cleft Palate - Craniofacial Journal. 2020 ; s. 352-363.

Bibtex

@article{caaa1efe45dd40a7bc5e5aae9c413677,
title = "Scandcleft Project Trial 3 – comparison of speech outcomes in relation to sequence in twostage palatal repair procedures in 5-year-olds with unilateral cleft lip and palate",
abstract = "Objective: To compare speech outcome following different sequencing of hard and soft palate closure between arms and centers within trial 3 and compare results to peers without cleft palate. Design: A prospective randomized clinical trial. Setting: Two Norwegian and 2 British centers. Participants: One hundred thirty-six 5-year-olds with unilateral cleft lip and palate were randomized to either lip and soft palate closure at 3 to 4 months and hard palate closure at 12 months (arm A) or lip and hard palate closure at 3 to 4 months and soft palate closure at 12 months (arm D). Main Outcome Measures: A composite measure of velopharyngeal competence (VPC), overall assessment of VPC from connected speech (VPC-Rate). Percentage of consonants correct (PCC), active cleft speech characteristics (CSCs), subdivided by oral retracted and nonoral errors, and developmental speech characteristics (DSCs). Results: Across the trial, 47% had VPC, with no statistically significant difference between arms within or across centers. Thirty-eight percent achieved a PCC score of >90%, with no difference between arms or centers. In one center, significantly more children in arm A produced >3 active CSCs (P < .05). Across centers, there was a statistically significant difference in active CSCs (arm D), oral retracted CSCs (arm D), and DSCs (arms A and D). Conclusions: Less than half of the 5-year-olds achieved VPC and around one-third achieved age-appropriate PCC scores. Cleft speech characteristics were more common in arm A, but outcomes varied within and across centers. Thus, outcome of the same surgical method can vary substantially across centers. Keywords RCT, 2-stage procedures, UCLP, speech",
author = "Christina Persson and Julie Davies and Elisabeth Willadsen and Melanie Bowden and Christine Hayden and Ragnhild Aukner and Pedersen, {Nina Helen}",
year = "2020",
doi = "10.1177/1055665619896637",
language = "English",
pages = "352--363",
journal = "Cleft Palate - Craniofacial Journal",
issn = "1055-6656",
publisher = "Allen Press Inc.",

}

RIS

TY - JOUR

T1 - Scandcleft Project Trial 3 – comparison of speech outcomes in relation to sequence in twostage palatal repair procedures in 5-year-olds with unilateral cleft lip and palate

AU - Persson , Christina

AU - Davies, Julie

AU - Willadsen, Elisabeth

AU - Bowden, Melanie

AU - Hayden, Christine

AU - Aukner, Ragnhild

AU - Pedersen, Nina Helen

PY - 2020

Y1 - 2020

N2 - Objective: To compare speech outcome following different sequencing of hard and soft palate closure between arms and centers within trial 3 and compare results to peers without cleft palate. Design: A prospective randomized clinical trial. Setting: Two Norwegian and 2 British centers. Participants: One hundred thirty-six 5-year-olds with unilateral cleft lip and palate were randomized to either lip and soft palate closure at 3 to 4 months and hard palate closure at 12 months (arm A) or lip and hard palate closure at 3 to 4 months and soft palate closure at 12 months (arm D). Main Outcome Measures: A composite measure of velopharyngeal competence (VPC), overall assessment of VPC from connected speech (VPC-Rate). Percentage of consonants correct (PCC), active cleft speech characteristics (CSCs), subdivided by oral retracted and nonoral errors, and developmental speech characteristics (DSCs). Results: Across the trial, 47% had VPC, with no statistically significant difference between arms within or across centers. Thirty-eight percent achieved a PCC score of >90%, with no difference between arms or centers. In one center, significantly more children in arm A produced >3 active CSCs (P < .05). Across centers, there was a statistically significant difference in active CSCs (arm D), oral retracted CSCs (arm D), and DSCs (arms A and D). Conclusions: Less than half of the 5-year-olds achieved VPC and around one-third achieved age-appropriate PCC scores. Cleft speech characteristics were more common in arm A, but outcomes varied within and across centers. Thus, outcome of the same surgical method can vary substantially across centers. Keywords RCT, 2-stage procedures, UCLP, speech

AB - Objective: To compare speech outcome following different sequencing of hard and soft palate closure between arms and centers within trial 3 and compare results to peers without cleft palate. Design: A prospective randomized clinical trial. Setting: Two Norwegian and 2 British centers. Participants: One hundred thirty-six 5-year-olds with unilateral cleft lip and palate were randomized to either lip and soft palate closure at 3 to 4 months and hard palate closure at 12 months (arm A) or lip and hard palate closure at 3 to 4 months and soft palate closure at 12 months (arm D). Main Outcome Measures: A composite measure of velopharyngeal competence (VPC), overall assessment of VPC from connected speech (VPC-Rate). Percentage of consonants correct (PCC), active cleft speech characteristics (CSCs), subdivided by oral retracted and nonoral errors, and developmental speech characteristics (DSCs). Results: Across the trial, 47% had VPC, with no statistically significant difference between arms within or across centers. Thirty-eight percent achieved a PCC score of >90%, with no difference between arms or centers. In one center, significantly more children in arm A produced >3 active CSCs (P < .05). Across centers, there was a statistically significant difference in active CSCs (arm D), oral retracted CSCs (arm D), and DSCs (arms A and D). Conclusions: Less than half of the 5-year-olds achieved VPC and around one-third achieved age-appropriate PCC scores. Cleft speech characteristics were more common in arm A, but outcomes varied within and across centers. Thus, outcome of the same surgical method can vary substantially across centers. Keywords RCT, 2-stage procedures, UCLP, speech

U2 - 10.1177/1055665619896637

DO - 10.1177/1055665619896637

M3 - Journal article

C2 - 31928085

SP - 352

EP - 363

JO - Cleft Palate - Craniofacial Journal

JF - Cleft Palate - Craniofacial Journal

SN - 1055-6656

ER -

ID: 226222936