Resistance exercise-induced hypertrophy: A potential role for rapamycin-insensitive mTOR
Research output: Contribution to journal › Review › Research › peer-review
The mechanistic target of rapamycin (mTOR) exerts both rapamycin-sensitive and rapamycin-insensitive signaling events, and the rapamycin-sensitive components of mTOR signaling have been widely implicated in the pathway through which resistance exercise induces skeletal muscle hypertrophy. This review explores the hypothesis that rapamycin-insensitive components of mTOR signaling also contribute to this highly important process.
Summary: This review examines whether both rapamycin-sensitive, and rapamycin-insensitive, components of mTOR signaling contribute to the hypertrophic effects of resistance exercise.
Original language | English |
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Journal | Exercise and Sport Sciences Reviews |
Volume | 47 |
Issue number | 3 |
Pages (from-to) | 188-194 |
ISSN | 0091-6331 |
DOIs | |
Publication status | Published - 2019 |
- Faculty of Science - Exercise, Hypertrophy, Protein synthesis, mTOR, mTORC1, mTORC2, Rapamycin
Research areas
Links
- http://europepmc.org/articles/pmc6659995?pdf=render
Accepted author manuscript
ID: 214870916