The Mothers, Infants, and Lactation Quality (MILQ) Study: A multi-center collaboration
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- Allen et al_Current Development in Nutrition_2021_Vol 5(10)_nzab116
Final published version, 1.08 MB, PDF document
Little valid information is available on human milk nutrient concentrations, especially for micronutrients (MNs), and there are no valid reference values (RVs) across lactation. In this multi-center collaborative study, RVs will be established for human milk nutrients across the first 8.5 mo postpartum. Well-nourished, unsupplemented women in Bangladesh, Brazil, Denmark, and The Gambia (n = 250/site) were recruited during the third trimester of pregnancy. Milk, blood, saliva, urine, and stool samples from mothers and their infants are collected identically at 3 visits (1-3.49, 3.5-5.99, 6.0-8.49 mo postpartum). Milk analyses include macronutrients, selected vitamins, trace elements and minerals, iodine, metabolomics, amino acids, human milk oligosaccharides, and bioactive peptides. We measure milk volume; maternal and infant diets, anthropometry, and morbidity; infant development, maternal genome, and the infant and maternal microbiome. RVs will be constructed based on methods for the WHO Child Growth Standards and the Intergrowth-21st Project.
This trial was registered at clinical trials.gov as NCT03254329.
Original language | English |
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Article number | nzab116 |
Journal | Current Developments in Nutrition |
Volume | 5 |
Issue number | 10 |
Number of pages | 14 |
DOIs | |
Publication status | Published - 2021 |
Bibliographical note
© The Author(s) 2021. Published by Oxford University Press on behalf of the American Society for Nutrition.
- Faculty of Science - Human milk, Macronutrients, Micronutrients, Composistion, Reference values
Research areas
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