What is the profile of overweight individuals who are unsuccessful responders to a low-energy diet? A PREVIEW sub-study
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What is the profile of overweight individuals who are unsuccessful responders to a low-energy diet? A PREVIEW sub-study. / Tremblay, Angelo; Fogelholm, Mikael; Jalo, Elli; Westerterp-Plantenga, Margriet S; Adam, Tanja C; Huttunen-Lenz, Maija; Stratton, Gareth; Lam, Tony; Handjieva-Darlenska, Teodora; Handjiev, Svetoslav; Martinez, J Alfredo; Macdonald, Ian A; Simpson, Elizabeth J; Brand-Miller, Jennie; Muirhead, Roslyn; Poppitt, Sally D; Silvestre, Marta P; Larsen, Thomas Meinert; Vestentoft, Pia Siig; Schlicht, Wolfgang; Drapeau, Vicky; Raben, Anne.
In: Frontiers in Nutrition, Vol. 8, 707682, 2021.Research output: Contribution to journal › Journal article › Research › peer-review
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T1 - What is the profile of overweight individuals who are unsuccessful responders to a low-energy diet? A PREVIEW sub-study
AU - Tremblay, Angelo
AU - Fogelholm, Mikael
AU - Jalo, Elli
AU - Westerterp-Plantenga, Margriet S
AU - Adam, Tanja C
AU - Huttunen-Lenz, Maija
AU - Stratton, Gareth
AU - Lam, Tony
AU - Handjieva-Darlenska, Teodora
AU - Handjiev, Svetoslav
AU - Martinez, J Alfredo
AU - Macdonald, Ian A
AU - Simpson, Elizabeth J
AU - Brand-Miller, Jennie
AU - Muirhead, Roslyn
AU - Poppitt, Sally D
AU - Silvestre, Marta P
AU - Larsen, Thomas Meinert
AU - Vestentoft, Pia Siig
AU - Schlicht, Wolfgang
AU - Drapeau, Vicky
AU - Raben, Anne
N1 - CURIS 2021 NEXS 341
PY - 2021
Y1 - 2021
N2 - This study was performed to evaluate the profile of overweight individuals withpre-diabetes enrolled in PREVIEW who were unable to achieve a body weight lossof ≥8% of the baseline value in response to a 2-month low-energy diet (LED). Their baseline profile reflected potential stress-related vulnerability that predicted a reduced response of body weight to a LED programme. The mean daily energy deficit maintained by unsuccessful weight responders of both sexes was less than the estimated level in successful female (656 vs. 1,299 kcal, p < 0.01) and male (815 vs. 1,659 kcal, p < 0.01) responders. Despite this smaller energy deficit, unsuccessful responders displayed less favorable changes in susceptibility to hunger and appetite sensations. They also did not benefit from the intervention regarding the ability to improve sleep quality. In summary, these results show that some individuals display a behavioral vulnerability which mayreduce the ability to lose weight in response to a diet-based weight loss program. They also suggest that this vulnerability may be accentuated by a prolonged diet restriction.
AB - This study was performed to evaluate the profile of overweight individuals withpre-diabetes enrolled in PREVIEW who were unable to achieve a body weight lossof ≥8% of the baseline value in response to a 2-month low-energy diet (LED). Their baseline profile reflected potential stress-related vulnerability that predicted a reduced response of body weight to a LED programme. The mean daily energy deficit maintained by unsuccessful weight responders of both sexes was less than the estimated level in successful female (656 vs. 1,299 kcal, p < 0.01) and male (815 vs. 1,659 kcal, p < 0.01) responders. Despite this smaller energy deficit, unsuccessful responders displayed less favorable changes in susceptibility to hunger and appetite sensations. They also did not benefit from the intervention regarding the ability to improve sleep quality. In summary, these results show that some individuals display a behavioral vulnerability which mayreduce the ability to lose weight in response to a diet-based weight loss program. They also suggest that this vulnerability may be accentuated by a prolonged diet restriction.
KW - Faculty of Science
KW - Obesity
KW - Behavior
KW - Energy
KW - Hunger
KW - Appetite
KW - Sleep
U2 - 10.3389/fnut.2021.707682
DO - 10.3389/fnut.2021.707682
M3 - Journal article
C2 - 34796192
VL - 8
JO - Frontiers in Nutrition
JF - Frontiers in Nutrition
SN - 2296-861X
M1 - 707682
ER -
ID: 284424726