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Synthesis of new isoxazoline-based acidic amino acids and investigation of their affinity and selectivity profile at ionotropic glutamate receptors. / Pinto, Andrea; Conti, Paola; Grazioso, Giovanni; Tamborini, Lucia; Madsen, Ulf; Nielsen, Birgitte; De Micheli, Carlo.
I:
European Journal of Medicinal Chemistry, Bind 46, Nr. 2, 01.02.2011, s. 787-793.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
Pinto, A, Conti, P, Grazioso, G, Tamborini, L
, Madsen, U, Nielsen, B & De Micheli, C 2011, '
Synthesis of new isoxazoline-based acidic amino acids and investigation of their affinity and selectivity profile at ionotropic glutamate receptors',
European Journal of Medicinal Chemistry, bind 46, nr. 2, s. 787-793.
https://doi.org/10.1016/j.ejmech.2010.12.020
APA
Pinto, A., Conti, P., Grazioso, G., Tamborini, L.
, Madsen, U., Nielsen, B., & De Micheli, C. (2011).
Synthesis of new isoxazoline-based acidic amino acids and investigation of their affinity and selectivity profile at ionotropic glutamate receptors.
European Journal of Medicinal Chemistry,
46(2), 787-793.
https://doi.org/10.1016/j.ejmech.2010.12.020
Vancouver
Pinto A, Conti P, Grazioso G, Tamborini L
, Madsen U, Nielsen B o.a.
Synthesis of new isoxazoline-based acidic amino acids and investigation of their affinity and selectivity profile at ionotropic glutamate receptors.
European Journal of Medicinal Chemistry. 2011 feb. 1;46(2):787-793.
https://doi.org/10.1016/j.ejmech.2010.12.020
Author
Pinto, Andrea ; Conti, Paola ; Grazioso, Giovanni ; Tamborini, Lucia ; Madsen, Ulf ; Nielsen, Birgitte ; De Micheli, Carlo. / Synthesis of new isoxazoline-based acidic amino acids and investigation of their affinity and selectivity profile at ionotropic glutamate receptors. I: European Journal of Medicinal Chemistry. 2011 ; Bind 46, Nr. 2. s. 787-793.
Bibtex
@article{c836c439ef524b24b97bbbb541cf1bae,
title = "Synthesis of new isoxazoline-based acidic amino acids and investigation of their affinity and selectivity profile at ionotropic glutamate receptors",
abstract = "The synthesis of four new isoxazoline-based amino acids being analogues of previously described glutamate receptor ligands is reported and their affinity for ionotropic glutamate receptors is analyzed in comparison with that of selected model compounds. Molecular modelling investigations have been carried out to rationalize the interaction with the NMDA receptors.",
keywords = "Former Faculty of Pharmaceutical Sciences",
author = "Andrea Pinto and Paola Conti and Giovanni Grazioso and Lucia Tamborini and Ulf Madsen and Birgitte Nielsen and {De Micheli}, Carlo",
note = "Keywords: glutamic acid, ionotropic Glu receptors, isoxazoline, 1,3-dipolar cycloaddition",
year = "2011",
month = feb,
day = "1",
doi = "10.1016/j.ejmech.2010.12.020",
language = "English",
volume = "46",
pages = "787--793",
journal = "European Journal of Medicinal Chemistry",
issn = "0223-5234",
publisher = "Elsevier Masson",
number = "2",
}
RIS
TY - JOUR
T1 - Synthesis of new isoxazoline-based acidic amino acids and investigation of their affinity and selectivity profile at ionotropic glutamate receptors
AU - Pinto, Andrea
AU - Conti, Paola
AU - Grazioso, Giovanni
AU - Tamborini, Lucia
AU - Madsen, Ulf
AU - Nielsen, Birgitte
AU - De Micheli, Carlo
N1 - Keywords: glutamic acid, ionotropic Glu receptors, isoxazoline, 1,3-dipolar cycloaddition
PY - 2011/2/1
Y1 - 2011/2/1
N2 - The synthesis of four new isoxazoline-based amino acids being analogues of previously described glutamate receptor ligands is reported and their affinity for ionotropic glutamate receptors is analyzed in comparison with that of selected model compounds. Molecular modelling investigations have been carried out to rationalize the interaction with the NMDA receptors.
AB - The synthesis of four new isoxazoline-based amino acids being analogues of previously described glutamate receptor ligands is reported and their affinity for ionotropic glutamate receptors is analyzed in comparison with that of selected model compounds. Molecular modelling investigations have been carried out to rationalize the interaction with the NMDA receptors.
KW - Former Faculty of Pharmaceutical Sciences
U2 - 10.1016/j.ejmech.2010.12.020
DO - 10.1016/j.ejmech.2010.12.020
M3 - Journal article
C2 - 21220180
VL - 46
SP - 787
EP - 793
JO - European Journal of Medicinal Chemistry
JF - European Journal of Medicinal Chemistry
SN - 0223-5234
IS - 2
ER -